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ProbPFP: a multiple sequence alignment algorithm combining hidden Markov model optimized by particle swarm optimization with partition function

BACKGROUND: During procedures for conducting multiple sequence alignment, that is so essential to use the substitution score of pairwise alignment. To compute adaptive scores for alignment, researchers usually use Hidden Markov Model or probabilistic consistency methods such as partition function. R...

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Detalles Bibliográficos
Autores principales: Zhan, Qing, Wang, Nan, Jin, Shuilin, Tan, Renjie, Jiang, Qinghua, Wang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876095/
https://www.ncbi.nlm.nih.gov/pubmed/31760933
http://dx.doi.org/10.1186/s12859-019-3132-7

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