DNA methylation aging clocks: challenges and recommendations

Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure subject age. These clocks are acknowledged as a highly accurate molecular correlate of chronological age in humans and other vertebrates. Also, extensive research is aimed at their potential to quantify biological agi...

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Detalles Bibliográficos
Autores principales: Bell, Christopher G., Lowe, Robert, Adams, Peter D., Baccarelli, Andrea A., Beck, Stephan, Bell, Jordana T., Christensen, Brock C., Gladyshev, Vadim N., Heijmans, Bastiaan T., Horvath, Steve, Ideker, Trey, Issa, Jean-Pierre J., Kelsey, Karl T., Marioni, Riccardo E., Reik, Wolf, Relton, Caroline L., Schalkwyk, Leonard C., Teschendorff, Andrew E., Wagner, Wolfgang, Zhang, Kang, Rakyan, Vardhman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876109/
https://www.ncbi.nlm.nih.gov/pubmed/31767039
http://dx.doi.org/10.1186/s13059-019-1824-y

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