FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/TGF-β/β-catenin pathway

BACKGROUND: Fibroblast growth factor (FGF) and tumor growth factor-β (TGFβ) have emerged as pivotal regulators during the progression of osteosarcoma (OS). LHX9 is one crucial transcription factor controlled by FGF, however, its function in OS has not been investigated yet. METHODS: The expression o...

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Detalles Bibliográficos
Autores principales: Li, Shuang-Qing, Tu, Chao, Wan, Lu, Chen, Rui-Qi, Duan, Zhi-Xi, Ren, Xiao-Lei, Li, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876112/
https://www.ncbi.nlm.nih.gov/pubmed/31788020
http://dx.doi.org/10.1186/s13008-019-0056-6

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