Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome

Pyridoxal 5′-phosphate (PLP) is a versatile cofactor that catalyzes a plethora of chemical transformations within a cell. Although many human PLP-dependent enzymes (PLP-DEs) with crucial physiological and pathological roles are known, a global method enabling their cellular profiling is lacking. Her...

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Detalles Bibliográficos
Autores principales: Fux, Anja, Pfanzelt, Martin, Kirsch, Volker C., Hoegl, Annabelle, Sieber, Stephan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876276/
https://www.ncbi.nlm.nih.gov/pubmed/31447350
http://dx.doi.org/10.1016/j.chembiol.2019.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876276/
https://www.ncbi.nlm.nih.gov/pubmed/31447350
http://dx.doi.org/10.1016/j.chembiol.2019.08.003

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