Cargando…

Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome

Pyridoxal 5′-phosphate (PLP) is a versatile cofactor that catalyzes a plethora of chemical transformations within a cell. Although many human PLP-dependent enzymes (PLP-DEs) with crucial physiological and pathological roles are known, a global method enabling their cellular profiling is lacking. Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fux, Anja, Pfanzelt, Martin, Kirsch, Volker C., Hoegl, Annabelle, Sieber, Stephan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876276/ https://www.ncbi.nlm.nih.gov/pubmed/31447350 http://dx.doi.org/10.1016/j.chembiol.2019.08.003

Ejemplares similares

Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics
por: Hoegl, Annabelle, et al.
Publicado: (2018)

Biochemical and Proteomic Studies of Human Pyridoxal 5′-Phosphate-Binding Protein (PLPBP)
por: Fux, Anja, et al.
Publicado: (2019)

Functionalised Cofactor Mimics for Interactome Discovery and Beyond
por: Wilkinson, Isabel V. L., et al.
Publicado: (2022)

Tailored Pyridoxal Probes Unravel Novel Cofactor‐Dependent Targets and Antibiotic Hits in Critical Bacterial Pathogens
por: Pfanzelt, Martin, et al.
Publicado: (2022)

Pyridoxal 5′-Phosphate Is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase
por: Ghatge, Mohini S., et al.
Publicado: (2012)

Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate
por: Filipowicz, A, et al.
Publicado: (2012)

Enzyme-independent catabolism of cysteine with pyridoxal-5′-phosphate
por: Mulay, Prajakatta, et al.
Publicado: (2023)

yggS Encoding Pyridoxal 5′-Phosphate Binding Protein Is Required for Acidovorax citrulli Virulence
por: Wang, Yuanjie, et al.
Publicado: (2022)

Crystal Structure and Pyridoxal 5-Phosphate Binding Property of Lysine Decarboxylase from Selenomonas ruminantium
por: Sagong, Hye-Young, et al.
Publicado: (2016)

Association of Serum Pyridoxal-5′-Phosphate, Pyridoxal, and PAr with Colorectal Cancer Risk: A Large-Scale Case-Control Study
por: Xu, Lei, et al.
Publicado: (2022)

Plasma Pyridoxal 5´-Phosphate Level in Children with Intractable and Controlled Epilepsy
por: PIRZADEH, Zahra, et al.
Publicado: (2017)

Pyridoxal-5′-Phosphate-Dependent Alkyl Transfer in Nucleoside Antibiotic Biosynthesis
por: Cui, Zheng, et al.
Publicado: (2020)

PDXK mutations cause polyneuropathy responsive to pyridoxal 5′‐phosphate supplementation
por: Chelban, Viorica, et al.
Publicado: (2019)

Identification and characterization of the pyridoxal 5’-phosphate allosteric site in Escherichia coli pyridoxine 5’-phosphate oxidase
por: Barile, Anna, et al.
Publicado: (2021)

Inactive mutants of human pyridoxine 5′‐phosphate oxidase: a possible role for a noncatalytic pyridoxal 5′‐phosphate tight binding site
por: Ghatge, Mohini S., et al.
Publicado: (2016)

carba Nicotinamide Adenine Dinucleotide Phosphate: Robust Cofactor for Redox Biocatalysis
por: Zachos, Ioannis, et al.
Publicado: (2021)

Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme
por: Dajnowicz, Steven, et al.
Publicado: (2017)

Current Advances on Structure-Function Relationships of Pyridoxal 5′-Phosphate-Dependent Enzymes
por: Liang, Jing, et al.
Publicado: (2019)

Comparative genomics of pyridoxal 5′-phosphate-dependent transcription factor regulons in Bacteria
por: Suvorova, Inna A., et al.
Publicado: (2016)

Pyridoxal 5′-Phosphate-Dependent Enzymes at the Crossroads of Host–Microbe Tryptophan Metabolism
por: Cellini, Barbara, et al.
Publicado: (2020)

Oxygen reactivity with pyridoxal 5′-phosphate enzymes: biochemical implications and functional relevance
por: Bisello, Giovanni, et al.
Publicado: (2020)

Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2
por: Tramonti, Angela, et al.
Publicado: (2021)

Preparation and characterization of an imogolite/chitosan hybrid with pyridoxal-5′-phosphate as an interfacial modifier
por: Mukai, Masaru, et al.
Publicado: (2021)

Association of Pyridoxal 5′-Phosphate with Sleep-Related Problems in a General Population
por: Ge, Lin, et al.
Publicado: (2022)

Complexation of Gold(III) with Pyridoxal 5′-Phosphate-Derived Hydrazones in Aqueous Solution
por: Kuranova, Natalia N., et al.
Publicado: (2022)

Comparative Proteomic Analysis for a Putative Pyridoxal Phosphate-Dependent Aminotransferase Required for Virulence in Acidovorax citrulli
por: Lee, Jongchan, et al.
Publicado: (2021)

Proteomic and Phenotypic Analyses of a Putative YggS Family Pyridoxal Phosphate-Dependent Enzyme in Acidovorax citrulli
por: Heo, Lynn, et al.
Publicado: (2023)

The Conserved Family of the Pyridoxal Phosphate-Binding Protein (PLPBP) and Its Cyanobacterial Paradigm PipY
por: Tremiño, Lorena, et al.
Publicado: (2022)

Supramolecular Tandem Assay for Pyridoxal‐5′‐phosphate by the Reporter Pair of Guanidinocalix[5]Arene and Fluorescein
por: Yue, Yu‐Xin, et al.
Publicado: (2019)

Native Microbiome Members of C. elegans Act Synergistically in Biosynthesis of Pyridoxal 5′-Phosphate
por: Haçariz, Orçun, et al.
Publicado: (2022)

Versatility of Pyridoxal Phosphate as a Coating of Iron Oxide Nanoparticles
por: Bonvin, Debora, et al.
Publicado: (2017)

Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability
por: Tramonti, Angela, et al.
Publicado: (2022)

It Takes Two to Tango: Defining an Essential Second Active Site in Pyridoxal 5′-Phosphate Synthase
por: Moccand, Cyril, et al.
Publicado: (2011)

Lysine Decarboxylase with an Enhanced Affinity for Pyridoxal 5-Phosphate by Disulfide Bond-Mediated Spatial Reconstitution
por: Sagong, Hye-Young, et al.
Publicado: (2017)

Application of the deep learning algorithm in nutrition research – using serum pyridoxal 5′-phosphate as an example
por: Ma, Chaoran, et al.
Publicado: (2022)

Pyridoxal 5′-phosphate alleviates prenatal pyridaben exposure-induced anxiety-like behaviors in offspring
por: Ding, Xingwang, et al.
Publicado: (2022)

Pyridoxal 5’-phosphate synthesis and salvage in Bacteria and Archaea: predicting pathway variant distributions and holes
por: Denise, Rémi, et al.
Publicado: (2023)

A Novel Two-Dimensional Liquid Chromatography Combined with Ultraviolet Detection Method for Quantitative Determination of Pyridoxal 5′-Phosphate, 4-Pyridoxine Acid and Pyridoxal in Animal Plasma
por: Yang, Rong-Ju, et al.
Publicado: (2023)

Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5′-phosphate synthesis
por: Kim, Juhan, et al.
Publicado: (2010)

A Survey of Pyridoxal 5′-Phosphate-Dependent Proteins in the Gram-Positive Model Bacterium Bacillus subtilis
por: Richts, Björn, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_go0kgee7sj2kumo8d0h1iml4ef