Prognosis and outcome of patients with acute myeloid leukemia based on FLT3-ITD mutation with or without additional abnormal cytogenetics

The FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) gene mutation is present in ~20% of patients with de novo acute myeloid leukemia (AML). Patients with an FLT3-ITD mutation have a poor prognosis. However, the prognostic function of FLT3-ITD combined with other cytogenetic abnorma...

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Autores principales: Tao, Shandong, Wang, Chunling, Chen, Yue, Deng, Yuan, Song, Lixiao, Shi, Yuyue, Ling, Lanlan, Ding, Banghe, He, Zhengmei, Yu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876342/
https://www.ncbi.nlm.nih.gov/pubmed/31807186
http://dx.doi.org/10.3892/ol.2019.11051

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