Synergy between Cyclase-associated protein and Cofilin accelerates actin filament depolymerization by two orders of magnitude

Cellular actin networks can be rapidly disassembled and remodeled in a few seconds, yet in vitro actin filaments depolymerize slowly over minutes. The cellular mechanisms enabling actin to depolymerize this fast have so far remained obscure. Using microfluidics-assisted TIRF, we show that Cyclase-as...

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Detalles Bibliográficos
Autores principales: Shekhar, Shashank, Chung, Johnson, Kondev, Jane, Gelles, Jeff, Goode, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876572/
https://www.ncbi.nlm.nih.gov/pubmed/31757952
http://dx.doi.org/10.1038/s41467-019-13268-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876572/
https://www.ncbi.nlm.nih.gov/pubmed/31757952
http://dx.doi.org/10.1038/s41467-019-13268-1

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