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Icariin Alleviates IL-1β-Induced Matrix Degradation By Activating The Nrf2/ARE Pathway In Human Chondrocytes
OBJECTIVE: Osteoarthritis (OA) is characterized by progressive matrix destruction of articular cartilage. This study aimed to investigate the potential antioxidative and chondroprotective effects and underlying mechanism of Icariin (ICA) in interleukin-1 beta (IL-1β)-induced extracellular matrix (EC...
Autores principales: | Zuo, Shi, Zou, Wei, Wu, Rong-Min, Yang, Jing, Fan, Jian-Nan, Zhao, Xue-Ke, Li, Hai-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876636/ https://www.ncbi.nlm.nih.gov/pubmed/31819369 http://dx.doi.org/10.2147/DDDT.S203094 |
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