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Statistical determination of synergy based on Bliss definition of drugs independence

Although synergy is a pillar of modern pharmacology, toxicology, and medicine, there is no consensus on its definition despite its nearly one hundred-year history. Moreover, methods for statistical determination of synergy that account for variation of response to treatment are underdeveloped and if...

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Detalles Bibliográficos
Autores principales: Demidenko, Eugene, Miller, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876842/
https://www.ncbi.nlm.nih.gov/pubmed/31765385
http://dx.doi.org/10.1371/journal.pone.0224137