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GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses

Dendritic cell (DC) activation is a critical step for anti-tumor T cell responses. Certain chemotherapeutics can influence DC function. Here we demonstrate that chemotherapy capable of microtubule destabilization has direct effects on DC function; namely, it induces potent DC maturation and elicits...

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Detalles Bibliográficos
Autores principales:	Kashyap, Abhishek S., Fernandez-Rodriguez, Laura, Zhao, Yun, Monaco, Gianni, Trefny, Marcel P., Yoshida, Naohiro, Martin, Kea, Sharma, Ashwani, Olieric, Natacha, Shah, Pankaj, Stanczak, Michal, Kirchhammer, Nicole, Park, Sung-Moo, Wieckowski, Sebastien, Laubli, Heinz, Zagani, Rachid, Kasenda, Benjamin, Steinmetz, Michel O., Reinecker, Hans-Christian, Zippelius, Alfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876861/ https://www.ncbi.nlm.nih.gov/pubmed/31553907 http://dx.doi.org/10.1016/j.celrep.2019.08.057

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