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Maximum parsimony interpretation of chromatin capture experiments

We present a new approach to characterizing the global geometric state of chromatin from HiC data. Chromatin conformation capture techniques (3C, and its variants: 4C, 5C, HiC, etc.) probe the spatial structure of the genome by identifying physical contacts between genomic loci within the nuclear sp...

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Detalles Bibliográficos
Autores principales: Homouz, Dirar, Kudlicki, Andrzej S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876987/
https://www.ncbi.nlm.nih.gov/pubmed/31765406
http://dx.doi.org/10.1371/journal.pone.0225578