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Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid
AIMS: Evaluation of failure rate and outcomes between skin and muscle surgery and lamellar tarsectomy procedure in major trichiasis of the upper lid. DESIGN: Quasi-randomized clinical study. METHODS AND SUBJECTS: One hundred individuals with major trichiasis of the upper lid were enrolled and assign...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877448/ https://www.ncbi.nlm.nih.gov/pubmed/31819349 http://dx.doi.org/10.2147/OPTH.S210038 |
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author | Elbaklish, Khaled Hamdi Saleh, Safaa M Gomaa, Wael Adel |
author_facet | Elbaklish, Khaled Hamdi Saleh, Safaa M Gomaa, Wael Adel |
author_sort | Elbaklish, Khaled Hamdi |
collection | PubMed |
description | AIMS: Evaluation of failure rate and outcomes between skin and muscle surgery and lamellar tarsectomy procedure in major trichiasis of the upper lid. DESIGN: Quasi-randomized clinical study. METHODS AND SUBJECTS: One hundred individuals with major trichiasis of the upper lid were enrolled and assigned to either skin and muscle surgery (group A) or a lamellar tarsectomy procedure (group B). Participants were examined at 6 and 12 months. The primary outcome measure (failure rate) was the percentage of participants having five or more eyelashes touching the globe or having surgery performed at any follow-up time in both groups. The secondary outcomes included failure time and changes in both visual acuity and corneal opacity. RESULTS: Risk failure over 6 months was 40% in group A and 10% in group B. Absolute risk reduction was 30% (95% CI=14.08–45.92%). Cumulative risk failure over 12 months was 20% in group A and 0.00% in group B after the second intervention. Absolute risk reduction was 20% (95% CI=8.58–31.42%). The number needed to treat (NNT) was 3.3 patients (95% CI=2.2–7.1). The mean number of rubbing lashes was greater in the skin and muscle group than in the lamellar tarsectomy group for 6 and 12 month examinations (0.002, 0.005). The change in visual acuity between the two groups was not significant. Recurrent trichiasis was noticed earlier, 6 weeks after surgery, in the skin and muscle group participants, and later, 3 months after surgery, in the lamellar tarsectomy group participants. CONCLUSION: The lamellar tarsectomy procedure is a good choice for management of major trichiasis of the upper lid. The subjective symptoms and lid margin conjunctivalization were improved in lamellar tarsectomy participants. Absence of new corneal opacity or a change in existing corneal opacification was noticed at the 12 months follow-up study. |
format | Online Article Text |
id | pubmed-6877448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-68774482019-12-09 Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid Elbaklish, Khaled Hamdi Saleh, Safaa M Gomaa, Wael Adel Clin Ophthalmol Original Research AIMS: Evaluation of failure rate and outcomes between skin and muscle surgery and lamellar tarsectomy procedure in major trichiasis of the upper lid. DESIGN: Quasi-randomized clinical study. METHODS AND SUBJECTS: One hundred individuals with major trichiasis of the upper lid were enrolled and assigned to either skin and muscle surgery (group A) or a lamellar tarsectomy procedure (group B). Participants were examined at 6 and 12 months. The primary outcome measure (failure rate) was the percentage of participants having five or more eyelashes touching the globe or having surgery performed at any follow-up time in both groups. The secondary outcomes included failure time and changes in both visual acuity and corneal opacity. RESULTS: Risk failure over 6 months was 40% in group A and 10% in group B. Absolute risk reduction was 30% (95% CI=14.08–45.92%). Cumulative risk failure over 12 months was 20% in group A and 0.00% in group B after the second intervention. Absolute risk reduction was 20% (95% CI=8.58–31.42%). The number needed to treat (NNT) was 3.3 patients (95% CI=2.2–7.1). The mean number of rubbing lashes was greater in the skin and muscle group than in the lamellar tarsectomy group for 6 and 12 month examinations (0.002, 0.005). The change in visual acuity between the two groups was not significant. Recurrent trichiasis was noticed earlier, 6 weeks after surgery, in the skin and muscle group participants, and later, 3 months after surgery, in the lamellar tarsectomy group participants. CONCLUSION: The lamellar tarsectomy procedure is a good choice for management of major trichiasis of the upper lid. The subjective symptoms and lid margin conjunctivalization were improved in lamellar tarsectomy participants. Absence of new corneal opacity or a change in existing corneal opacification was noticed at the 12 months follow-up study. Dove 2019-11-20 /pmc/articles/PMC6877448/ /pubmed/31819349 http://dx.doi.org/10.2147/OPTH.S210038 Text en © 2019 Elbaklish et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Elbaklish, Khaled Hamdi Saleh, Safaa M Gomaa, Wael Adel Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid |
title | Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid |
title_full | Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid |
title_fullStr | Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid |
title_full_unstemmed | Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid |
title_short | Lamellar Tarsectomy Procedure In Major Trichiasis Of The Upper Lid |
title_sort | lamellar tarsectomy procedure in major trichiasis of the upper lid |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877448/ https://www.ncbi.nlm.nih.gov/pubmed/31819349 http://dx.doi.org/10.2147/OPTH.S210038 |
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