Cargando…

Gastric acid inhibitor aggravates indomethacin-induced small intestinal injury via reducing Lactobacillus johnsonii

Proton pump inhibitors (PPIs) alter the composition of the intestinal microbiome, exacerbating indomethacin (IND)-induced small intestinal damage. Vonoprazan fumarate inhibits gastric acid secretion using a different mechanism from PPIs. We investigated the effects of both drugs on the intestinal mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nadatani, Yuji, Watanabe, Toshio, Suda, Wataru, Nakata, Akinobu, Matsumoto, Yuji, Kosaka, Satoshi, Higashimori, Akira, Otani, Koji, Hosomi, Shuhei, Tanaka, Fumio, Nagami, Yasuaki, Kamata, Noriko, Taira, Koichi, Yamagami, Hirokazu, Tanigawa, Tetsuya, Hattori, Masahira, Fujiwara, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877529/ https://www.ncbi.nlm.nih.gov/pubmed/31767915 http://dx.doi.org/10.1038/s41598-019-53559-7

Ejemplares similares

Rebamipide ameliorates indomethacin-induced small intestinal damage and proton pump inhibitor-induced exacerbation of this damage by modulation of small intestinal microbiota
por: Tanigawa, Tetsuya, et al.
Publicado: (2021)

Long-term persistence of gastric dysbiosis after eradication of Helicobacter pylori in patients who underwent endoscopic submucosal dissection for early gastric cancer
por: Watanabe, Toshio, et al.
Publicado: (2020)

Involvement of gliadin, a component of wheat gluten, in increased intestinal permeability leading to non-steroidal anti-inflammatory drug-induced small-intestinal damage
por: Shimada, Sunao, et al.
Publicado: (2019)

Utility of Kyoto Classification of Gastritis in subjects with a high-negative titer of anti-Helicobacter pylori antibody during a medical check-up
por: Otani, Koji, et al.
Publicado: (2020)

Protective role of resolvin D1, a pro-resolving lipid mediator, in nonsteroidal anti-inflammatory drug-induced small intestinal damage
por: Kuzumoto, Takuya, et al.
Publicado: (2021)

A Rare Case of Clival Metastasis in a Patient with Gastric Cancer
por: Yoshikawa-Kimura, Akie, et al.
Publicado: (2020)

Prevalence and risk factor for chronic diarrhea in participants of a Japanese medical checkup
por: Matsumoto, Yuji, et al.
Publicado: (2021)

Eosinophilic esophagitis and asymptomatic esophageal eosinophilia display similar immunohistological profiles
por: Kitamura, Hiroyuki, et al.
Publicado: (2021)

Psychological Stress Exacerbates Inflammation of the Ileum via the Corticotropin-Releasing Hormone-Mast Cell Axis in a Mouse Model of Eosinophilic Enteritis
por: Kanamori, Atsushi, et al.
Publicado: (2022)

Ovariectomy-Induced Dysbiosis May Have a Minor Effect on Bone in Mice
por: Kosaka, Satoshi, et al.
Publicado: (2021)

Acceptance of COVID-19 Vaccines among Patients with Inflammatory Bowel Disease in Japan
por: Nishida, Yu, et al.
Publicado: (2021)

Impact of the COVID-19 Pandemic on the Lifestyle and Psychosocial Behavior of Patients with Inflammatory Bowel Diseases: A Narrative Review
por: Nishida, Yu, et al.
Publicado: (2023)

Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene
por: Nakata, Rieko, et al.
Publicado: (2020)

Short bevacizumab infusion as an effective and safe treatment for colorectal cancer
por: Taira, Koichi, et al.
Publicado: (2022)

Pyogenic Spondylitis Caused by Staphylococcus schleiferi in a Patient with Crohn's Disease
por: Fujimoto, Koji, et al.
Publicado: (2021)

Sa077 DOES THE LOCKDOWN DUE TO COVID-19 PANDEMIC AFFECT THE LIFESTYLE AND DISEASE ACTIVITY OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE?
por: Hosomi, Shuhei, et al.
Publicado: (2021)

High-fat diet-mediated dysbiosis exacerbates NSAID-induced small intestinal damage through the induction of interleukin-17A
por: Sugimura, Naoki, et al.
Publicado: (2019)

Endoscopic findings of gastric lesions in patients with eosinophilic gastrointestinal disorders
por: Fujiwara, Yasuhiro, et al.
Publicado: (2020)

Effect of the Coronavirus Disease 2019 Lockdown on Lifestyle Factors in Japanese Patients with Inflammatory Bowel Disease
por: Nishida, Yu, et al.
Publicado: (2022)

Neutrophil-to-lymphocyte ratio may predict clinical relapse in ulcerative colitis patients with mucosal healing
por: Kurimoto, Noriyuki, et al.
Publicado: (2023)

Colchicine prevents NSAID-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome
por: Otani, Koji, et al.
Publicado: (2016)

Impact of the Lockdown Due to the COVID-19 Pandemic on Patients With Inflammatory Bowel Disease
por: Nishida, Yu, et al.
Publicado: (2021)

A mask-based infection control method for screening endoscopy may prevent SARS-CoV-2 transmission and relieve staff anxiety
por: Nadatani, Yuji, et al.
Publicado: (2021)

NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis
por: Itani, Shigehiro, et al.
Publicado: (2016)

The impact of cytochrome P450 3A genetic polymorphisms on tacrolimus pharmacokinetics in ulcerative colitis patients
por: Furuse, Maizumi, et al.
Publicado: (2021)

A questionnaire-based survey on the etiopathogenesis of chronic constipation during a medical check-up in Japan
por: Otani, Koji, et al.
Publicado: (2022)

Upper gastrointestinal endoscopic findings in functional constipation and irritable bowel syndrome diagnosed using the Rome IV criteria: a cross-sectional survey during a medical check-up in Japan
por: Otani, Koji, et al.
Publicado: (2023)

Comparison of the Diagnostic Efficiency of Radial- and Convex-Arrayed Echoendoscopes for Indirect Findings of Pancreatic Cancer: A Retrospective Comparative Study Using Propensity Score Method
por: Ishikawa-Kakiya, Yuki, et al.
Publicado: (2021)

Clinical Implication of Preoperative C-Reactive Protein/Albumin Ratio in Malignant Transformation of Intraductal Papillary Mucinous Neoplasm: A Propensity Score Analysis
por: Maruyama, Hirotsugu, et al.
Publicado: (2022)

Lustrous White Erosions Surrounded by an Erythematous Mucosa: A Novel Endoscopic Finding of Gastric Lesions in Patients with Wilson Disease
por: Kitagawa, Daiki, et al.
Publicado: (2021)

Novel prognostic biomarkers of pouchitis after ileal pouch-anal anastomosis for ulcerative colitis: Neutrophil-to-lymphocyte ratio
por: Nishida, Yu, et al.
Publicado: (2020)

Pretreatment neutrophil-to-lymphocyte ratio predicts clinical relapse of ulcerative colitis after tacrolimus induction
por: Nishida, Yu, et al.
Publicado: (2019)

The impact of COVID‐19 on Japanese patients with eosinophilic gastrointestinal disorders during the vaccination era
por: Fujiwara, Yasuhiro, et al.
Publicado: (2023)

Neutrophil-to-Lymphocyte Ratio for Predicting Loss of Response to Infliximab in Ulcerative Colitis
por: Nishida, Yu, et al.
Publicado: (2017)

Azathioprine Is Useful for Maintaining Long-term Remission Induced by Tacrolimus for the Treatment of Ulcerative Colitis: An Inverse Probability of a Treatment Weighing Analysis
por: Nishida, Yu, et al.
Publicado: (2019)

Expression of Serum Exosomal and Esophageal MicroRNA in Rat Reflux Esophagitis
por: Uemura, Risa, et al.
Publicado: (2017)

Angle of covered self-expandable metallic stents after placement is a risk factor for recurrent biliary obstruction
por: Tanoue, Kojiro, et al.
Publicado: (2022)

Repeated Endoscopic Submucosal Dissection for Esophageal Neoplasia Located Close to a Previous Endoscopic Submucosal Dissection Scar
por: Nagami, Yasuaki, et al.
Publicado: (2020)

Risk of pancreatitis after pancreatic duct guidewire placement during endoscopic retrograde cholangiopancreatography
por: Ishikawa-Kakiya, Yuki, et al.
Publicado: (2018)

Analysis of the Risk Factors of Surgery after Endoscopic Balloon Dilation for Small Intestinal Strictures in Crohn's Disease Using Double-balloon Endoscopy
por: Nishida, Yu, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_qr0fuhlhskbmrm97c73bm48513