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The Balance in T Follicular Helper Cell Subsets Is Altered in Neuromyelitis Optica Spectrum Disorder Patients and Restored by Rituximab

Neuromyelitis optica spectrum disorder (NMOSD) is a rare and severe auto-immune disease of the central nervous system driven by pathogenic antibodies mainly directed against aquaporin-4 (AQP4-Ab). Treatment of NMOSD currently relies on immunosuppressants (mycophenolate mofetil, azathioprine) or B-ce...

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Detalles Bibliográficos
Autores principales: Nicolas, Philippe, Ruiz, Anne, Cobo-Calvo, Alvaro, Fiard, Guillaume, Giraudon, Pascale, Vukusic, Sandra, Marignier, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877601/
https://www.ncbi.nlm.nih.gov/pubmed/31803192
http://dx.doi.org/10.3389/fimmu.2019.02686