m(6)A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2

Dynamic mRNA modification in the form of N(6)-methyladenosine (m(6)A) adds considerable richness and sophistication to gene regulation. The m(6)A mark is asymmetrically distributed along mature mRNAs, with approximately 35% of m(6)A residues located within the coding region (CDS). It has been sugges...

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Detalles Bibliográficos
Autores principales: Mao, Yuanhui, Dong, Leiming, Liu, Xiao-Min, Guo, Jiayin, Ma, Honghui, Shen, Bin, Qian, Shu-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877647/
https://www.ncbi.nlm.nih.gov/pubmed/31767846
http://dx.doi.org/10.1038/s41467-019-13317-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877647/
https://www.ncbi.nlm.nih.gov/pubmed/31767846
http://dx.doi.org/10.1038/s41467-019-13317-9

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