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m(6)A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
Dynamic mRNA modification in the form of N(6)-methyladenosine (m(6)A) adds considerable richness and sophistication to gene regulation. The m(6)A mark is asymmetrically distributed along mature mRNAs, with approximately 35% of m(6)A residues located within the coding region (CDS). It has been sugges...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877647/ https://www.ncbi.nlm.nih.gov/pubmed/31767846 http://dx.doi.org/10.1038/s41467-019-13317-9 |