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Naringenin Ameliorates Drosophila ReepA Hereditary Spastic Paraplegia-Linked Phenotypes

Defects in the endoplasmic reticulum (ER) membrane shaping and interaction with other organelles seem to be a crucial mechanism underlying Hereditary Spastic Paraplegia (HSP) neurodegeneration. REEP1, a transmembrane protein belonging to TB2/HVA22 family, is implicated in SPG31, an autosomal dominan...

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Detalles Bibliográficos
Autores principales:	Napoli, Barbara, Gumeni, Sentiljana, Forgiarini, Alessia, Fantin, Marianna, De Filippis, Concetta, Panzeri, Elena, Vantaggiato, Chiara, Orso, Genny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877660/ https://www.ncbi.nlm.nih.gov/pubmed/31803000 http://dx.doi.org/10.3389/fnins.2019.01202

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