Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)

Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell transplantation. Therapeutic strategies may differ between...

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Detalles Bibliográficos
Autores principales: Haddad, Elie, Hoenig, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877719/
https://www.ncbi.nlm.nih.gov/pubmed/31803700
http://dx.doi.org/10.3389/fped.2019.00481
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author Haddad, Elie
Hoenig, Manfred
author_facet Haddad, Elie
Hoenig, Manfred
author_sort Haddad, Elie
collection PubMed
description Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell transplantation. Therapeutic strategies may differ between subtypes and the inherent reduced capacity or inablility to reject a graft have to be considered.
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spelling pubmed-68777192019-12-04 Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID) Haddad, Elie Hoenig, Manfred Front Pediatr Pediatrics Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell transplantation. Therapeutic strategies may differ between subtypes and the inherent reduced capacity or inablility to reject a graft have to be considered. Frontiers Media S.A. 2019-11-19 /pmc/articles/PMC6877719/ /pubmed/31803700 http://dx.doi.org/10.3389/fped.2019.00481 Text en Copyright © 2019 Haddad and Hoenig. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Haddad, Elie
Hoenig, Manfred
Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)
title Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)
title_full Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)
title_fullStr Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)
title_full_unstemmed Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)
title_short Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)
title_sort hematopoietic stem cell transplantation for severe combined immunodeficiency (scid)
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877719/
https://www.ncbi.nlm.nih.gov/pubmed/31803700
http://dx.doi.org/10.3389/fped.2019.00481
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