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Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

BACKGROUND: Tbx18 is a vital transcription factor involved in embryonic sinoatrial node (SAN) formation process but is gradually vanished after birth. Myocardial injection of lentiviral Tbx18 converts cardiomyocytes into pacemaker-like cells morphologically and functionally. In this in vitro and in...

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Detalles Bibliográficos
Autores principales:	Hu, Yannan, Li, Ning, Liu, Liang, Zhang, Hao, Xue, Xiang, Shao, Xin, Zhang, Yu, Lang, Xilong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877911/ https://www.ncbi.nlm.nih.gov/pubmed/31814832 http://dx.doi.org/10.1155/2019/3621314

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