Cargando…

Oxidative DNA Damage Signalling in Neural Stem Cells in Alzheimer's Disease

The main pathological symptoms of Alzheimer's disease (AD) are β-amyloid (Aβ) lesions and intracellular neurofibrillary tangles of hyperphosphorylated tau protein. Unfortunately, existing symptomatic therapies targeting Aβ and tau remain ineffective. In addition to these pathogenic factors, oxi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kieroń, Marcelina, Żekanowski, Cezary, Falk, Anna, Wężyk, Michalina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877938/ https://www.ncbi.nlm.nih.gov/pubmed/31814869 http://dx.doi.org/10.1155/2019/2149812

Ejemplares similares

Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer's Disease
por: Wezyk, Michalina, et al.
Publicado: (2018)

Genetic studies of Polish migraine patients: screening for causative mutations in four migraine-associated genes
por: Domitrz, Izabela, et al.
Publicado: (2016)

The Impact of Mitochondrial DNA and Nuclear Genes Related to Mitochondrial Functioning on the Risk of Parkinson’s Disease
por: Gaweda-Walerych, Katarzyna, et al.
Publicado: (2013)

Oxidative Damage of DNA as Early Marker of Alzheimer’s Disease
por: Peña-Bautista, Carmen, et al.
Publicado: (2019)

PIN1 gene variants in Alzheimer's disease
por: Maruszak, Aleksandra, et al.
Publicado: (2009)

Contributions of DNA Damage to Alzheimer’s Disease
por: Lin, Xiaozeng, et al.
Publicado: (2020)

Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
por: Lovell, Mark A., et al.
Publicado: (2007)

Neural stem/progenitor cells in Alzheimer’s disease
por: Tincer, Gizem, et al.
Publicado: (2016)

DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups
por: Spólnicka, M., et al.
Publicado: (2017)

mTOR controls endoplasmic reticulum–Golgi apparatus trafficking of VSVg in specific cell types
por: Koscielny, Alicja, et al.
Publicado: (2021)

Altered plasma marker of oxidative DNA damage and total antioxidant capacity in patients with Alzheimer's disease
por: Moslemnezhad, Ameneh, et al.
Publicado: (2016)

Oxidative-Signaling in Neural Stem Cell-Mediated Plasticity: Implications for Neurodegenerative Diseases
por: dos Santos, Mafalda Ferreira, et al.
Publicado: (2021)

Association of ADORA1 rs2228079 and ADORA2A rs5751876 Polymorphisms with Gilles de la Tourette Syndrome in the Polish Population
por: Janik, Piotr, et al.
Publicado: (2015)

Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells
por: Falk, Ronny, et al.
Publicado: (2012)

Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?
por: Gonfloni, Stefania, et al.
Publicado: (2012)

Effects of neural stem cell transplantation in Alzheimer’s disease models
por: Hayashi, Yoshihito, et al.
Publicado: (2020)

DNA Damage in Mammalian Neural Stem Cells Leads to Astrocytic Differentiation Mediated by BMP2 Signaling through JAK-STAT
por: Schneider, Leonid, et al.
Publicado: (2013)

Redox-dependent Igfbp2 signaling controls Brca1 DNA damage response to govern neural stem cell fate
por: Shahin, Weam S., et al.
Publicado: (2023)

Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a “dominant-positive” mechanism
por: Walerych, Dawid, et al.
Publicado: (2018)

DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease
por: Wang, Heling, et al.
Publicado: (2021)

Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease
por: Silva, Aderbal R. T., et al.
Publicado: (2014)

HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology
por: Tanaka, Hikari, et al.
Publicado: (2021)

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease
por: Pao, Ping-Chieh, et al.
Publicado: (2020)

DNA Damage and Oxidative Stress in Human Disease
por: Maluf, Sharbel Weidner, et al.
Publicado: (2013)

KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease
por: Siddiqui, Tohid, et al.
Publicado: (2021)

Epigenetic regulation of adult neural stem cells: implications for Alzheimer’s disease
por: Fitzsimons, Carlos P, et al.
Publicado: (2014)

Mesenchymal and Neural Stem Cell-Derived Exosomes in Treating Alzheimer’s Disease
por: Wang, Hongmin, et al.
Publicado: (2023)

The Role of DNA Damage in Neural Plasticity in Physiology and Neurodegeneration
por: Konopka, Anna, et al.
Publicado: (2022)

XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells
por: Kulkarni, Avanti, et al.
Publicado: (2008)

A coordinated DNA damage response promotes adult quiescent neural stem cell activation
por: Barazzuol, Lara, et al.
Publicado: (2017)

The Role of Oxidative Damage in the Pathogenesis and Progression of Alzheimer's Disease and Vascular Dementia
por: Luca, Maria, et al.
Publicado: (2015)

The basic chemistry of exercise-induced DNA oxidation: oxidative damage, redox signaling, and their interplay
por: Cobley, James N., et al.
Publicado: (2015)

Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells
por: Kawanishi, Shosuke, et al.
Publicado: (2017)

Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency
por: Gaweda-Walerych, Katarzyna, et al.
Publicado: (2021)

Mitochondrial Deficits With Neural and Social Damage in Early-Stage Alzheimer’s Disease Model Mice
por: Misrani, Afzal, et al.
Publicado: (2021)

The Response to Oxidative DNA Damage in Neurons: Mechanisms and Disease
por: Narciso, Laura, et al.
Publicado: (2016)

Targeting β-secretase with RNAi in neural stem cells for Alzheimer's disease therapy
por: Liu, Zhonghua, et al.
Publicado: (2013)

Ganglioside-Dependent Neural Stem Cell Proliferation in Alzheimer’s Disease Model Mice
por: Koon, Noah A., et al.
Publicado: (2015)

Chiral Nanoparticles Force Neural Stem Cell Differentiation to Alleviate Alzheimer's Disease
por: Shi, Baimei, et al.
Publicado: (2022)

The therapeutic prospects and challenges of human neural stem cells for the treatment of Alzheimer's Disease
por: Yue, Chunmei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_scur4roetg0h62hije19dh59r6