Cargando…

Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example

Myeloid sarcoma (MS) is a rare myeloid malignancy. It can arise before, concurrent with, or following different malignant hematological diseases, most commonly acute myeloid leukemia (AML), myelodysplastic syndrome, or myeloproliferative neoplasms. Here we describe a 30‐year‐old female with AML‐M1 w...

Descripción completa

Detalles Bibliográficos
Autores principales: Khoshnaw, Najmaddin, Yassin, Ahmed K., Alwan, Alaa F., Hassan, Hemin A., Mula‐Hussain, Layth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878049/
https://www.ncbi.nlm.nih.gov/pubmed/31788245
http://dx.doi.org/10.1002/ccr3.2407
_version_ 1783473458140676096
author Khoshnaw, Najmaddin
Yassin, Ahmed K.
Alwan, Alaa F.
Hassan, Hemin A.
Mula‐Hussain, Layth
author_facet Khoshnaw, Najmaddin
Yassin, Ahmed K.
Alwan, Alaa F.
Hassan, Hemin A.
Mula‐Hussain, Layth
author_sort Khoshnaw, Najmaddin
collection PubMed
description Myeloid sarcoma (MS) is a rare myeloid malignancy. It can arise before, concurrent with, or following different malignant hematological diseases, most commonly acute myeloid leukemia (AML), myelodysplastic syndrome, or myeloproliferative neoplasms. Here we describe a 30‐year‐old female with AML‐M1 who presented to the hematology department with bilateral breast pain and tenderness. Available diagnostic measures including ultrasound of breast and magnetic resonance imaging were used to determine the nature of these breast lumps. MS was definitively diagnosed via biopsy and the patient was treated with systemic chemotherapy. Despite her AML treatment she unfortunately died secondary to disease progression. The authors consider this case of particular educational value due to the bilateral and aggressive nature of this patient’s disease in the setting of a cancer‐care facility with limited resources. KEY CLINICAL MESSAGE: In retrospect, if breast MS had been considered earlier in this patient’s presentation, a referral to an outside center with matched stem cell transplantation capability may have been warranted after complete remission following first bone marrow relapse, rather than continuing chemotherapy alone.
format Online
Article
Text
id pubmed-6878049
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-68780492019-11-29 Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example Khoshnaw, Najmaddin Yassin, Ahmed K. Alwan, Alaa F. Hassan, Hemin A. Mula‐Hussain, Layth Clin Case Rep Case Reports Myeloid sarcoma (MS) is a rare myeloid malignancy. It can arise before, concurrent with, or following different malignant hematological diseases, most commonly acute myeloid leukemia (AML), myelodysplastic syndrome, or myeloproliferative neoplasms. Here we describe a 30‐year‐old female with AML‐M1 who presented to the hematology department with bilateral breast pain and tenderness. Available diagnostic measures including ultrasound of breast and magnetic resonance imaging were used to determine the nature of these breast lumps. MS was definitively diagnosed via biopsy and the patient was treated with systemic chemotherapy. Despite her AML treatment she unfortunately died secondary to disease progression. The authors consider this case of particular educational value due to the bilateral and aggressive nature of this patient’s disease in the setting of a cancer‐care facility with limited resources. KEY CLINICAL MESSAGE: In retrospect, if breast MS had been considered earlier in this patient’s presentation, a referral to an outside center with matched stem cell transplantation capability may have been warranted after complete remission following first bone marrow relapse, rather than continuing chemotherapy alone. John Wiley and Sons Inc. 2019-09-16 /pmc/articles/PMC6878049/ /pubmed/31788245 http://dx.doi.org/10.1002/ccr3.2407 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Khoshnaw, Najmaddin
Yassin, Ahmed K.
Alwan, Alaa F.
Hassan, Hemin A.
Mula‐Hussain, Layth
Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example
title Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example
title_full Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example
title_fullStr Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example
title_full_unstemmed Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example
title_short Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example
title_sort challenges associated with limited‐resources cancer care facility: bilateral breast myeloid sarcoma as an example
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878049/
https://www.ncbi.nlm.nih.gov/pubmed/31788245
http://dx.doi.org/10.1002/ccr3.2407
work_keys_str_mv AT khoshnawnajmaddin challengesassociatedwithlimitedresourcescancercarefacilitybilateralbreastmyeloidsarcomaasanexample
AT yassinahmedk challengesassociatedwithlimitedresourcescancercarefacilitybilateralbreastmyeloidsarcomaasanexample
AT alwanalaaf challengesassociatedwithlimitedresourcescancercarefacilitybilateralbreastmyeloidsarcomaasanexample
AT hassanhemina challengesassociatedwithlimitedresourcescancercarefacilitybilateralbreastmyeloidsarcomaasanexample
AT mulahussainlayth challengesassociatedwithlimitedresourcescancercarefacilitybilateralbreastmyeloidsarcomaasanexample