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Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example
Myeloid sarcoma (MS) is a rare myeloid malignancy. It can arise before, concurrent with, or following different malignant hematological diseases, most commonly acute myeloid leukemia (AML), myelodysplastic syndrome, or myeloproliferative neoplasms. Here we describe a 30‐year‐old female with AML‐M1 w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878049/ https://www.ncbi.nlm.nih.gov/pubmed/31788245 http://dx.doi.org/10.1002/ccr3.2407 |
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author | Khoshnaw, Najmaddin Yassin, Ahmed K. Alwan, Alaa F. Hassan, Hemin A. Mula‐Hussain, Layth |
author_facet | Khoshnaw, Najmaddin Yassin, Ahmed K. Alwan, Alaa F. Hassan, Hemin A. Mula‐Hussain, Layth |
author_sort | Khoshnaw, Najmaddin |
collection | PubMed |
description | Myeloid sarcoma (MS) is a rare myeloid malignancy. It can arise before, concurrent with, or following different malignant hematological diseases, most commonly acute myeloid leukemia (AML), myelodysplastic syndrome, or myeloproliferative neoplasms. Here we describe a 30‐year‐old female with AML‐M1 who presented to the hematology department with bilateral breast pain and tenderness. Available diagnostic measures including ultrasound of breast and magnetic resonance imaging were used to determine the nature of these breast lumps. MS was definitively diagnosed via biopsy and the patient was treated with systemic chemotherapy. Despite her AML treatment she unfortunately died secondary to disease progression. The authors consider this case of particular educational value due to the bilateral and aggressive nature of this patient’s disease in the setting of a cancer‐care facility with limited resources. KEY CLINICAL MESSAGE: In retrospect, if breast MS had been considered earlier in this patient’s presentation, a referral to an outside center with matched stem cell transplantation capability may have been warranted after complete remission following first bone marrow relapse, rather than continuing chemotherapy alone. |
format | Online Article Text |
id | pubmed-6878049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-68780492019-11-29 Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example Khoshnaw, Najmaddin Yassin, Ahmed K. Alwan, Alaa F. Hassan, Hemin A. Mula‐Hussain, Layth Clin Case Rep Case Reports Myeloid sarcoma (MS) is a rare myeloid malignancy. It can arise before, concurrent with, or following different malignant hematological diseases, most commonly acute myeloid leukemia (AML), myelodysplastic syndrome, or myeloproliferative neoplasms. Here we describe a 30‐year‐old female with AML‐M1 who presented to the hematology department with bilateral breast pain and tenderness. Available diagnostic measures including ultrasound of breast and magnetic resonance imaging were used to determine the nature of these breast lumps. MS was definitively diagnosed via biopsy and the patient was treated with systemic chemotherapy. Despite her AML treatment she unfortunately died secondary to disease progression. The authors consider this case of particular educational value due to the bilateral and aggressive nature of this patient’s disease in the setting of a cancer‐care facility with limited resources. KEY CLINICAL MESSAGE: In retrospect, if breast MS had been considered earlier in this patient’s presentation, a referral to an outside center with matched stem cell transplantation capability may have been warranted after complete remission following first bone marrow relapse, rather than continuing chemotherapy alone. John Wiley and Sons Inc. 2019-09-16 /pmc/articles/PMC6878049/ /pubmed/31788245 http://dx.doi.org/10.1002/ccr3.2407 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Khoshnaw, Najmaddin Yassin, Ahmed K. Alwan, Alaa F. Hassan, Hemin A. Mula‐Hussain, Layth Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example |
title | Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example |
title_full | Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example |
title_fullStr | Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example |
title_full_unstemmed | Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example |
title_short | Challenges associated with limited‐resources cancer care facility: Bilateral breast myeloid sarcoma as an example |
title_sort | challenges associated with limited‐resources cancer care facility: bilateral breast myeloid sarcoma as an example |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878049/ https://www.ncbi.nlm.nih.gov/pubmed/31788245 http://dx.doi.org/10.1002/ccr3.2407 |
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