Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs

A 60‐year‐old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC‐ACT) causing induction of anti‐oncogenic and anti‐PD‐L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC‐ACT, metastases have been arrested, and the patient reports good...

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Autores principales: Chinami, Masanobu, Iwabuchi, Kaoru, Muto, Yoshiteru, Uchida, Yasuhiko, Arita, Ryu, Shuraim, Rana A., Adra, Chaker N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878052/
https://www.ncbi.nlm.nih.gov/pubmed/31788270
http://dx.doi.org/10.1002/ccr3.2343
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author Chinami, Masanobu
Iwabuchi, Kaoru
Muto, Yoshiteru
Uchida, Yasuhiko
Arita, Ryu
Shuraim, Rana A.
Adra, Chaker N.
author_facet Chinami, Masanobu
Iwabuchi, Kaoru
Muto, Yoshiteru
Uchida, Yasuhiko
Arita, Ryu
Shuraim, Rana A.
Adra, Chaker N.
author_sort Chinami, Masanobu
collection PubMed
description A 60‐year‐old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC‐ACT) causing induction of anti‐oncogenic and anti‐PD‐L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC‐ACT, metastases have been arrested, and the patient reports good quality of life.
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spelling pubmed-68780522019-11-29 Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs Chinami, Masanobu Iwabuchi, Kaoru Muto, Yoshiteru Uchida, Yasuhiko Arita, Ryu Shuraim, Rana A. Adra, Chaker N. Clin Case Rep Case Reports A 60‐year‐old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC‐ACT) causing induction of anti‐oncogenic and anti‐PD‐L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC‐ACT, metastases have been arrested, and the patient reports good quality of life. John Wiley and Sons Inc. 2019-09-30 /pmc/articles/PMC6878052/ /pubmed/31788270 http://dx.doi.org/10.1002/ccr3.2343 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Chinami, Masanobu
Iwabuchi, Kaoru
Muto, Yoshiteru
Uchida, Yasuhiko
Arita, Ryu
Shuraim, Rana A.
Adra, Chaker N.
Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs
title Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs
title_full Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs
title_fullStr Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs
title_full_unstemmed Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs
title_short Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs
title_sort assessment by mirna microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (ac‐act) approach; demonstrated induction of anti‐oncogenic and anti‐pd‐l1 mirnas
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878052/
https://www.ncbi.nlm.nih.gov/pubmed/31788270
http://dx.doi.org/10.1002/ccr3.2343
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