Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature

HLH is a catastrophic and likely underdiagnosed pathology with multiple triggers including infection. PVB19 can cause persistent marrow infection leading to HLH despite negative acute serologic markers making timely diagnosis difficult. Increased awareness of PVB19‐HLH is warranted given its potenti...

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Detalles Bibliográficos
Autores principales: Kalmuk, James, Matar, Sara, Feng, Gong, Kilb, Edward, Lim, Ming Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878072/
https://www.ncbi.nlm.nih.gov/pubmed/31788255
http://dx.doi.org/10.1002/ccr3.2401
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author Kalmuk, James
Matar, Sara
Feng, Gong
Kilb, Edward
Lim, Ming Y.
author_facet Kalmuk, James
Matar, Sara
Feng, Gong
Kilb, Edward
Lim, Ming Y.
author_sort Kalmuk, James
collection PubMed
description HLH is a catastrophic and likely underdiagnosed pathology with multiple triggers including infection. PVB19 can cause persistent marrow infection leading to HLH despite negative acute serologic markers making timely diagnosis difficult. Increased awareness of PVB19‐HLH is warranted given its potentially lethal nature and the careful interpretation required with serologic markers.
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spelling pubmed-68780722019-11-29 Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature Kalmuk, James Matar, Sara Feng, Gong Kilb, Edward Lim, Ming Y. Clin Case Rep Case Reports HLH is a catastrophic and likely underdiagnosed pathology with multiple triggers including infection. PVB19 can cause persistent marrow infection leading to HLH despite negative acute serologic markers making timely diagnosis difficult. Increased awareness of PVB19‐HLH is warranted given its potentially lethal nature and the careful interpretation required with serologic markers. John Wiley and Sons Inc. 2019-09-27 /pmc/articles/PMC6878072/ /pubmed/31788255 http://dx.doi.org/10.1002/ccr3.2401 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Kalmuk, James
Matar, Sara
Feng, Gong
Kilb, Edward
Lim, Ming Y.
Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature
title Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature
title_full Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature
title_fullStr Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature
title_full_unstemmed Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature
title_short Parvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature
title_sort parvovirus b19‐induced hemophagocytic lymphohistiocytosis: case report and review of the literature
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878072/
https://www.ncbi.nlm.nih.gov/pubmed/31788255
http://dx.doi.org/10.1002/ccr3.2401
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