LPS-Induced Systemic Neonatal Inflammation: Blockage of P2X7R by BBG Decreases Mortality on Rat Pups and Oxidative Stress in Hippocampus of Adult Rats

Neonatal lipopolysaccharide (LPS) exposure-induced brain inflammation has been associated to neuronal injury and facilitates the development of models of neurological disorders in adult rats. The P2X7 receptor (P2X7R) plays a fundamental role in the onset and maintenance of the inflammatory cascade....

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Detalles Bibliográficos
Autores principales: da Silva, Clivandir Severino, Calió, Michele Longoni, Mosini, Amanda Cristina, Pires, Jaime Moreira, Rêgo, Débora da Silva Bandeira, Mello, Luiz E., Leslie, Ana Teresa Figueiredo Stochero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878118/
https://www.ncbi.nlm.nih.gov/pubmed/31798427
http://dx.doi.org/10.3389/fnbeh.2019.00240

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