ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

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[Image: see text] ABHD2 is a serine hydrolase that belongs to the subgroup of the α,β-hydrolase fold-containing proteins, which is involved in virus propagation, immune response, and fertilization. Chemical tools to selectively modulate the activity of ABHD2 in an acute setting are highly desired to...

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Detalles Bibliográficos
Autores principales: Baggelaar, Marc P., den Dulk, Hans, Florea, Bogdan I., Fazio, Domenico, Bernabò, Nicola, Raspa, Marcello, Janssen, Antonius P. A., Scavizzi, Ferdinando, Barboni, Barbara, Overkleeft, Hermen S., Maccarrone, Mauro, van der Stelt, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878212/
https://www.ncbi.nlm.nih.gov/pubmed/31525885
http://dx.doi.org/10.1021/acschembio.9b00640
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