Mono-institutional phase 2 study of innovative Stereotactic Body RadioTherapy targeting PArtial Tumor HYpoxic (SBRT-PATHY) clonogenic cells in unresectable bulky non-small cell lung cancer: profound non-targeted effects by sparing peri-tumoral immune microenvironment

BACKGROUND: Radiotherapy-induced lymphopenia may be limiting the success of therapy and could also negatively affect the ability of immune system in mediating the bystander (BE) and abscopal effects (AE). A novel SBRT-based PArtial Tumor irradiation of HYpoxic clonogenic cells (SBRT-PATHY) for induc...

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Detalles Bibliográficos
Autores principales: Tubin, Slavisa, Khan, Mohammad K., Salerno, Gerardo, Mourad, Waleed F., Yan, Weisi, Jeremic, Branislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878646/
https://www.ncbi.nlm.nih.gov/pubmed/31771654
http://dx.doi.org/10.1186/s13014-019-1410-1

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