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Mucoadhesive Particles: A Novel, Prolonged-Release Nanocarrier of Sitagliptin for the Treatment of Diabetics
Sitagliptin (MK–0431) is a widely and commonly used oral hypoglycemic drug in the treatment of type 2 diabetes mellitus; patients typically take higher doses of this drug (50 mg, twice daily). One drawback is that only 38% of the drug is bound reversibly to plasma proteins and 79% is excreted in uri...
Autores principales: | SreeHarsha, Nagaraja, Ramnarayanan, Chandramouli, Al-Dhubiab, Bandar E., Nair, Anroop B., Hiremath, Jagadeesh G., Venugopala, Katharigatta N., Satish, Roopashree T., Attimarad, Mahesh, Shariff, Arshia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878770/ https://www.ncbi.nlm.nih.gov/pubmed/31815135 http://dx.doi.org/10.1155/2019/3950942 |
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