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Opposing Pressures of Speed and Efficiency Guide the Evolution of Molecular Machines

Many biomolecular machines need to be both fast and efficient. How has evolution optimized these machines along the tradeoff between speed and efficiency? We explore this question using optimizable dynamical models along coordinates that are plausible evolutionary degrees of freedom. Data on 11 moto...

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Detalles Bibliográficos
Autores principales: Wagoner, Jason A, Dill, Ken A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878954/
https://www.ncbi.nlm.nih.gov/pubmed/31432071
http://dx.doi.org/10.1093/molbev/msz190

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