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Opposing Pressures of Speed and Efficiency Guide the Evolution of Molecular Machines
Many biomolecular machines need to be both fast and efficient. How has evolution optimized these machines along the tradeoff between speed and efficiency? We explore this question using optimizable dynamical models along coordinates that are plausible evolutionary degrees of freedom. Data on 11 moto...
Autores principales: | Wagoner, Jason A, Dill, Ken A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878954/ https://www.ncbi.nlm.nih.gov/pubmed/31432071 http://dx.doi.org/10.1093/molbev/msz190 |
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