TIGAR Promotes Tumorigenesis and Protects Tumor Cells From Oxidative and Metabolic Stresses in Gastric Cancer

Cancer cells adopt glycolysis to facilitate the generation of biosynthetic substrates demanded by cell proliferation and growth, and to adapt to stress conditions such as excessive reactive oxygen species (ROS) accumulation. TIGAR (TP53-induced glycolysis and apoptosis regulator) is a fructose-2,6-b...

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Detalles Bibliográficos
Autores principales: Liu, Zhenhua, Wu, Yue, Zhang, Yingqiu, Yuan, Menglang, Li, Xuelu, Gao, Jiyue, Zhang, Shanni, Xing, Chengjuan, Qin, Huamin, Zhao, Hongbo, Zhao, Zuowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878961/
https://www.ncbi.nlm.nih.gov/pubmed/31799200
http://dx.doi.org/10.3389/fonc.2019.01258

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