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Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands

Endothelium‐derived C‐type natriuretic peptide possesses cytoprotective and anti‐atherogenic functions that regulate vascular homeostasis. The vasoprotective effects of C‐type natriuretic peptide are somewhat mediated by the natriuretic peptide receptor C, suggesting that this receptor represents a...

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Detalles Bibliográficos
Autores principales:	Conole, Daniel, Myers, Samuel H., Mota, Filipa, Hobbs, Adrian J., Selwood, David L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Screen Development and Drug Discovery Approaches
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879014/ https://www.ncbi.nlm.nih.gov/pubmed/30218492 http://dx.doi.org/10.1111/cbdd.13395

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