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Unified Approach to the Chemoselective α-Functionalization of Amides with Heteroatom Nucleophiles
[Image: see text] Functionalization at the α-position of carbonyl compounds has classically relied on enolate chemistry. As a result, the generation of a new C–X bond, where X is more electronegative than carbon requires an oxidation event. Herein we show that, by rendering the α-position of amides...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879173/ https://www.ncbi.nlm.nih.gov/pubmed/31714077 http://dx.doi.org/10.1021/jacs.9b06956 |