Comprehensive Genome Analysis of Carbapenem-Resistant Strains of Raoultella Species, an Emerging Multidrug-Resistant Bacterium in Hospitals

We report the characterization of six carbapenem-resistant Raoultella spp. (CRRS) in our hospital and a genomic analysis of 58 publicly available isolates. CRRS isolates are sporadically identified around the world, and different transposons carrying carbapenemases were the resistant mechanisms. Mob...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Xiao, Zheng, Beiwen, Zhang, Jing, Xu, Hao, Xiao, Tingting, Zhou, Yanzi, Zhang, Shuntian, Zhu, Yunying, Wang, Yuan, Xiao, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879265/
https://www.ncbi.nlm.nih.gov/pubmed/31570399
http://dx.doi.org/10.1128/AAC.01367-19
Descripción
Sumario:We report the characterization of six carbapenem-resistant Raoultella spp. (CRRS) in our hospital and a genomic analysis of 58 publicly available isolates. CRRS isolates are sporadically identified around the world, and different transposons carrying carbapenemases were the resistant mechanisms. Mobile genetic elements play an important role in acquiring antibiotic resistance genes from the hospital. An improved understanding of these transposon and targeted control measures will be very valuable to prevent CRRS dissemination.

Ejemplares similares