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Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading

Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are a major class of lipid-anchored plasma membrane proteins. GPI-APs form nanoclusters generated by cortical acto-myosin activity. While our understanding of the physical principles governing this process is emerging, the molecular machinery...

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Detalles Bibliográficos
Autores principales: Kalappurakkal, Joseph Mathew, Anilkumar, Anupama Ambika, Patra, Chandrima, van Zanten, Thomas S., Sheetz, Michael P., Mayor, Satyajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879320/
https://www.ncbi.nlm.nih.gov/pubmed/31104842
http://dx.doi.org/10.1016/j.cell.2019.04.037