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Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T

Cortical hyperexcitability has been found in early Amyotrophic Lateral Sclerosis (ALS) and is hypothesized to be a key factor in pathogenesis. The current pilot study aimed to investigate cortical inhibitory/excitatory balance in ALS using short-echo Magnetic Resonance Spectroscopy (MRS). Patients s...

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Detalles Bibliográficos
Autores principales: Blicher, J. U., Eskildsen, S. F., Stærmose, T. G., Møller, A. T., Figlewski, K., Near, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879471/
https://www.ncbi.nlm.nih.gov/pubmed/31772352
http://dx.doi.org/10.1038/s41598-019-53009-4