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On-target restoration of a split T cell-engaging antibody for precision immunotherapy

T cell-engaging immunotherapies are changing the landscape of current cancer care. However, suitable target antigens are scarce, restricting these strategies to very few tumor types. Here, we report on a T cell-engaging antibody derivative that comes in two complementary halves and addresses antigen...

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Detalles Bibliográficos
Autores principales:	Banaszek, Agnes, Bumm, Thomas G. P., Nowotny, Boris, Geis, Maria, Jacob, Kim, Wölfl, Matthias, Trebing, Johannes, Kucka, Kirstin, Kouhestani, Dina, Gogishvili, Tea, Krenz, Bastian, Lutz, Justina, Rasche, Leo, Hönemann, Dirk, Neuweiler, Hannes, Heiby, Julia C., Bargou, Ralf C., Wajant, Harald, Einsele, Hermann, Riethmüller, Gert, Stuhler, Gernot
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879491/ https://www.ncbi.nlm.nih.gov/pubmed/31772172 http://dx.doi.org/10.1038/s41467-019-13196-0

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