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Effect of imbalance in folate and vitamin B12 in maternal/parental diet on global methylation and regulatory miRNAs

DNA methylation, a central component of the epigenetic network is altered in response to nutritional influences. In one-carbon cycle, folate acts as a one-carbon carrier and vitamin B12 acts as co-factor for the enzyme methionine synthase. Both folate and vitamin B12 are the important regulators of...

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Detalles Bibliográficos
Autores principales: Mahajan, Aatish, Sapehia, Divika, Thakur, Shilpa, Mohanraj, Palani Selvam, Bagga, Rashmi, Kaur, Jyotdeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879517/
https://www.ncbi.nlm.nih.gov/pubmed/31772242
http://dx.doi.org/10.1038/s41598-019-54070-9