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Effect of imbalance in folate and vitamin B12 in maternal/parental diet on global methylation and regulatory miRNAs
DNA methylation, a central component of the epigenetic network is altered in response to nutritional influences. In one-carbon cycle, folate acts as a one-carbon carrier and vitamin B12 acts as co-factor for the enzyme methionine synthase. Both folate and vitamin B12 are the important regulators of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879517/ https://www.ncbi.nlm.nih.gov/pubmed/31772242 http://dx.doi.org/10.1038/s41598-019-54070-9 |