Cargando…
A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out
There is a constant need for new therapeutic compounds. Fungi have proven to be an excellent, but underexplored source for biologically active compounds with therapeutic potential. Here, we combine mycology, embryology and chemistry by testing secondary metabolites from more than 10,000 species of f...
Autores principales: | Hoeksma, Jelmer, Misset, Tim, Wever, Christie, Kemmink, Johan, Kruijtzer, John, Versluis, Kees, Liskamp, Rob M. J., Boons, Geert Jan, Heck, Albert J. R., Boekhout, Teun, den Hertog, Jeroen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879544/ https://www.ncbi.nlm.nih.gov/pubmed/31772307 http://dx.doi.org/10.1038/s41598-019-54127-9 |
Ejemplares similares
-
Loss of Shp1 impairs myeloid cell function and causes lethal inflammation in zebrafish larvae
por: Allers, Maaike, et al.
Publicado: (2023) -
Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish
por: Hoeksma, Jelmer, et al.
Publicado: (2020) -
Evolution-Informed Discovery of the Naphthalenone Biosynthetic Pathway in Fungi
por: Mosunova, Olga V., et al.
Publicado: (2022) -
Gregatins, a Group of Related Fungal Secondary Metabolites, Inhibit Aspects of Quorum Sensing in Gram-Negative Bacteria
por: Beenker, Wouter A. G., et al.
Publicado: (2022) -
A peptide mimic of the chemotaxis inhibitory protein of Staphylococcus aureus: towards the development of novel anti-inflammatory compounds
por: Bunschoten, Anton, et al.
Publicado: (2010)