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Pneumococcal Polysaccharide Vaccine Ameliorates Murine Lupus

Current guidelines encourage administering pneumococcal vaccine Prevnar-13 to patients with lupus, but whether such vaccinations affect disease severity is unclear. To address this issue, we treated 3-month-old MRL-lpr mice, that spontaneously develop a lupus-like syndrome, with Prevnar-13 or vehicl...

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Detalles Bibliográficos
Autores principales: Cantarelli, Chiara, Guglielmo, Chiara, Hartzell, Susan, Salem, Fadi El, Andrighetto, Sofia, Gazivoda, Victor P., Fiaccadori, Enrico, La Manna, Gaetano, Zaza, Gianluigi, Leventhal, Jeremy, Tassiulas, Ioannis, Cravedi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879550/
https://www.ncbi.nlm.nih.gov/pubmed/31824490
http://dx.doi.org/10.3389/fimmu.2019.02695