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Deepprune: Learning Efficient and Interpretable Convolutional Networks Through Weight Pruning for Predicting DNA-Protein Binding

Convolutional neural network (CNN) based methods have outperformed conventional machine learning methods in predicting the binding preference of DNA-protein binding. Although studies in the past have shown that more convolutional kernels help to achieve better performance, visualization of the model...

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Detalles Bibliográficos
Autores principales: Luo, Xiao, Chi, Weilai, Deng, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879555/
https://www.ncbi.nlm.nih.gov/pubmed/31824562
http://dx.doi.org/10.3389/fgene.2019.01145