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Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling
Potassium channels are presumed to have two allosterically coupled gates, the activation gate and the selectivity filter gate, that control channel opening, closing, and inactivation. However, the molecular mechanism of how these gates regulate K(+ )ion flow through the channel remains poorly unders...
Autores principales: | Kopec, Wojciech, Rothberg, Brad S., de Groot, Bert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879586/ https://www.ncbi.nlm.nih.gov/pubmed/31772184 http://dx.doi.org/10.1038/s41467-019-13227-w |
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