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The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma

Glioblastoma Multiforme (GBM) is the most common and aggressive primary brain tumor. Despite recent developments in surgery, chemo- and radio-therapy, a currently poor prognosis of GBM patients highlights an urgent need for novel treatment strategies. TRAIL (TNF Related Apoptosis Inducing Ligand) is...

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Detalles Bibliográficos
Autores principales: Ozyerli-Goknar, Ezgi, Sur-Erdem, Ilknur, Seker, Fidan, Cingöz, Ahmet, Kayabolen, Alisan, Kahya-Yesil, Zeynep, Uyulur, Fırat, Gezen, Melike, Tolay, Nazife, Erman, Batu, Gönen, Mehmet, Dunford, James, Oppermann, Udo, Bagci-Onder, Tugba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879621/
https://www.ncbi.nlm.nih.gov/pubmed/31772153
http://dx.doi.org/10.1038/s41419-019-2107-y