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The Actin-Capping Protein Alpha-Adducin Is Required for T-Cell Costimulation

Alpha-adducin (Add1) is a critical component of the actin-spectrin network in erythrocytes, acting to cap the fast-growing, barbed ends of actin filaments, and recruiting spectrin to these junctions. Add1 is highly expressed in T cells, but its role in T-cell activation has not been examined. Using...

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Detalles Bibliográficos
Autores principales: Thauland, Timothy J., Khan, Humza A., Butte, Manish J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879651/
https://www.ncbi.nlm.nih.gov/pubmed/31824498
http://dx.doi.org/10.3389/fimmu.2019.02706