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Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma

The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial, with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered candidates. Here, by using genetically engineered mouse models and organoids, we assessed the tumor-forming properties of...

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Detalles Bibliográficos
Autores principales:	Zhang, Shuang, Dolgalev, Igor, Zhang, Tao, Ran, Hao, Levine, Douglas A., Neel, Benjamin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879755/ https://www.ncbi.nlm.nih.gov/pubmed/31772167 http://dx.doi.org/10.1038/s41467-019-13116-2

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