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Erlotinib overcomes paclitaxel-resistant cancer stem cells by blocking the EGFR-CREB/GRβ-IL-6 axis in MUC1-positive cervical cancer
Cancer stem cells (CSCs) are often enriched after chemotherapy and contribute to tumor relapse. While epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are widely used for the treatment of diverse types of cancer, whether EGFR-TKIs are effective against chemoresistant CSCs in...
Autores principales: | Lv, Yaping, Cang, Wei, Li, Quanfu, Liao, Xiaodong, Zhan, Mengna, Deng, Huayun, Li, Shengze, Jin, Wei, Pang, Zhi, Qiu, Xingdi, Zhao, Kewen, Chen, Guoqiang, Qiu, Lihua, Huang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879758/ https://www.ncbi.nlm.nih.gov/pubmed/31772161 http://dx.doi.org/10.1038/s41389-019-0179-2 |
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