Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies

Glioblastoma persists as a uniformly deadly diagnosis for patients and effective therapeutic options are gravely needed. Recently, targeted gene therapy approaches are reemerging as attractive experimental clinical agents. Our ligand-directed hybrid virus of adeno-associated virus and phage (AAVP) i...

Descripción completa

Detalles Bibliográficos
Autores principales: Staquicini, Fernanda I., Smith, Tracey L., Tang, Fenny H. F., Gelovani, Juri G., Giordano, Ricardo J., Libutti, Steven K., Sidman, Richard L., Cavenee, Webster K., Arap, Wadih, Pasqualini, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879804/
https://www.ncbi.nlm.nih.gov/pubmed/31130731
http://dx.doi.org/10.1038/s41417-019-0101-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879804/
https://www.ncbi.nlm.nih.gov/pubmed/31130731
http://dx.doi.org/10.1038/s41417-019-0101-2

Ejemplares similares