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Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies

Glioblastoma persists as a uniformly deadly diagnosis for patients and effective therapeutic options are gravely needed. Recently, targeted gene therapy approaches are reemerging as attractive experimental clinical agents. Our ligand-directed hybrid virus of adeno-associated virus and phage (AAVP) i...

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Detalles Bibliográficos
Autores principales:	Staquicini, Fernanda I., Smith, Tracey L., Tang, Fenny H. F., Gelovani, Juri G., Giordano, Ricardo J., Libutti, Steven K., Sidman, Richard L., Cavenee, Webster K., Arap, Wadih, Pasqualini, Renata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879804/ https://www.ncbi.nlm.nih.gov/pubmed/31130731 http://dx.doi.org/10.1038/s41417-019-0101-2

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