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Measuring Transcription at a Single Gene Copy Reveals Hidden Drivers of Bacterial Individuality

Single-cell measurements of mRNA copy-number inform our understanding of stochastic gene expression [1-3], but these measurements coarse-grain over the individual copies of the gene, where transcription and its regulation stochastically take plasce [4, 5]. Here we combine single-molecule quantificat...

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Detalles Bibliográficos
Autores principales: Wang, Mengyu, Zhang, Jing, Xu, Heng, Golding, Ido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879826/
https://www.ncbi.nlm.nih.gov/pubmed/31527794
http://dx.doi.org/10.1038/s41564-019-0553-z

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