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Measuring Transcription at a Single Gene Copy Reveals Hidden Drivers of Bacterial Individuality
Single-cell measurements of mRNA copy-number inform our understanding of stochastic gene expression [1-3], but these measurements coarse-grain over the individual copies of the gene, where transcription and its regulation stochastically take plasce [4, 5]. Here we combine single-molecule quantificat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879826/ https://www.ncbi.nlm.nih.gov/pubmed/31527794 http://dx.doi.org/10.1038/s41564-019-0553-z |