Acetaldehyde induces phosphorylation of dynamin-related protein 1 and mitochondrial dysfunction via elevating intracellular ROS and Ca(2+) levels

Excessive alcohol consumption impairs brain function and has been associated with an earlier onset of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). Acetaldehyde, the most toxic metabolite of alcohol, has been speculated to mediate the neurotoxici...

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Detalles Bibliográficos
Autores principales: Yan, Tingting, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879985/
https://www.ncbi.nlm.nih.gov/pubmed/31756635
http://dx.doi.org/10.1016/j.redox.2019.101381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879985/
https://www.ncbi.nlm.nih.gov/pubmed/31756635
http://dx.doi.org/10.1016/j.redox.2019.101381

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