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Amyloid-β oligomers suppress subunit-specific glutamate receptor increase during LTP
INTRODUCTION: Amyloid-β oligomers (AβOs) are assumed to impair the ability of learning and memory by suppressing the induction of synaptic plasticity, such as long-term potentiation (LTP) in the early stage of Alzheimer's disease. However, the direct molecular mechanism of how AβOs affect excit...
Autores principales: | Tanaka, Hiromitsu, Sakaguchi, Daiki, Hirano, Tomoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880111/ https://www.ncbi.nlm.nih.gov/pubmed/31788535 http://dx.doi.org/10.1016/j.trci.2019.10.003 |
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