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Amyloid-β oligomers suppress subunit-specific glutamate receptor increase during LTP

INTRODUCTION: Amyloid-β oligomers (AβOs) are assumed to impair the ability of learning and memory by suppressing the induction of synaptic plasticity, such as long-term potentiation (LTP) in the early stage of Alzheimer's disease. However, the direct molecular mechanism of how AβOs affect excit...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiromitsu, Sakaguchi, Daiki, Hirano, Tomoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880111/
https://www.ncbi.nlm.nih.gov/pubmed/31788535
http://dx.doi.org/10.1016/j.trci.2019.10.003

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