Enhanced Therapeutic Efficacy of a Novel Oncolytic Herpes Simplex Virus Type 2 Encoding an Antibody Against Programmed Cell Death 1

The efficacy of immune checkpoint blockade therapy against immunologically “cold” tumors can be enhanced by applying the checkpoint inhibitors in combination with oncolytic viruses. Alternatively, the oncolytic virus construct has been modified to express factors that boost oncolytic virus function....

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yujie, Hu, Xiao, Feng, Lin, Yang, Zhenrong, Zhou, Lulin, Duan, Xinchun, Cheng, Shujun, Zhang, Wen, Liu, Binlei, Zhang, Kaitai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880119/
https://www.ncbi.nlm.nih.gov/pubmed/31788554
http://dx.doi.org/10.1016/j.omto.2019.10.003

Ejemplares similares

Ejemplares similares